Methotrexate issue

[LesJames]

I have been using MTX injections for 5+ years now. On Friday I proceeded with my usual routine, just after the injection I got a very sharp pain like a bee sting on the site of entry. I rubbed it but did not look at the site however it continued to sting. The following day I still had the pain and decided to look, I was surprised to see an area of 3" x 1" very red and raised it was painful to touch and still is to this day. Has anyone else had a situation like this?

I have been to the minor clinic and contacted my consultant, with no answer yet. I believe the needle did not go into the muscle but the surrounding area causing a burn under the skin. Anyone else got an idea?

[oldtimer2]

Methotrexate can be given as a subcutaneous or intramuscular injection - it depends which device you're using.

It looks as if you might have caught a small blood vessel, or you have a small histamine reaction. The latter might be more of a problem if it continues or increases. I'd see what happens next time?

[J1707-]

yep every now and then I hit a blood vessel or a nerve . Really had some spectacular bruises or marks

[Bootoo]

I think we all get them from time to time, I wouldn't worry too much unless it's painful. I had one on my stomach which lasted weeks.

[medway-lady]

I had an injection of Gentamyacin in the thigh and two days later was rolling on the floor in agony.Red, swollen like an egg and so painful. Rang 111 got sent to A &E and the doctor said, the doctor who did the injection had gone into the small vein and it has bleed into muscle. It was measured and they said if it got bigger they would remove the clot otherwise it’s time. So give it another day or two. Luckily two days latter same size so no need to operate. Lesson was never let a doctor give an injection into thigh as they aren’t too good at them. lol x Ice and pain relief was given in A&E that did really help.

[LesJames]

Saw my doctor tonight, who went,”wow” when he saw it. He thinks it is a Cytotoxic reaction. Just waiting on blood tests