methotrexate injection stinging

[Pepperpot22]

Never had any issue with methotrexate injections before, but my latest supply sting like hell! All around the injection site for a gud 5-10 mins after. Just me, or has anyone else noticed a difference recently?

[Boxerlady]

Yes, the new ones do sting a bit whereas the old ones were painless. I find that it lasts less than a minute, though.

[Spanelmad]

Try using San I've cube to numb the site before injecting

[virtualreality]

Yes same! Even the new style injections were ok, but my latest batch has been more stingy for some reason. Hopefully the next batch will be back to normal.

[Pepperpot22 in reply to virtualreality]

Yes, that’s exactly like me! I’ve been using the new style for a while with no problems. It’s only since my last prescription that it’s happened!

[CagneysMum]

Sometimes my injections sting and sometimes not … not sure what causes it but it never lasts more than an hour.

[SunshineSmiles1]

It is entirely possible that the manufacturer has added something new to the formulation. I react really badly to sulphite preservatives for example and they sting like crazy. It might be worth checking the full ingredient list to see if you can spot anything new.

[Pepperpot22 in reply to SunshineSmiles1]

Gud idea. Hadn’t thought to check that!

[PCStrawberry]

There are preservatives used in many injectable solutions, particularly those where multiple doses are drawn from a single vial. They ensure a safe product, but most of them will sting a bit. It's a lesser of evils, better a hot moment than an infection.

[Pepperpot22 in reply to PCStrawberry]

I agree!

[Thingybob]

I noticed this too.Also get a yellow 'ink blot' stain under my skin around the site about 5 mins after my injection. Its gone by the next morning. I asked the rheumy nurse who suggested holding it in longer and presding harder but it still does it.

[Pepperpot22 in reply to Thingybob]

I haven’t noticed an ‘ink blot’ stain but will look closer nxt week!

[Gottarelax]

Yes, I find the stinging lasts about 5 min. I used to prefer injections to swallowing pills but now I'm not so sure. I have to brace myself for what feels like a wasp sting. I also find I bruise more often at the site of injection too.

[Pepperpot22 in reply to Gottarelax]

Seems I’m not the only one by the replies I’ve had. Wonder if it’s a one off batch? 🤷‍♀️

[Gaz227]

I’m finding it’s a bit hit and miss , some sting done don’t , I guess it comes down to the quality in the manufacturing

[Lovemygrapes]

Hi, yes I am having the same problem, stinging around the injection site for at least 10 minutes, never used to bother me taking my injection but now dred taking it 😩

[Pepperpot22 in reply to Lovemygrapes]

Yes, hav to grit our teeth & hope the nxt batch is better! 😂

[Pamela-bsl]

I find the same with adalimumab