methotrexate injections and atorvastatin statin - NRAS

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methotrexate injections and atorvastatin statin

Gladjake profile image
14 Replies

hi everyone I’m still panicking about taking my statin,been prescribed 10mg atorvastatin daily .geared myself up to take them (bit of a wimp with medication🤦‍♀️) pharmacist said to discuss with doctor before taking them as can cause some sort of toxicity when on methotrexate,and may need more frequent blood tests

Doctor knows I’m on methotrexate so sure it should be ok.anyone else on this combination.

thanks

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Gladjake profile image
Gladjake
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14 Replies
helixhelix profile image
helixhelix

have been taking methotrexate and simvastatin for years

julie01 profile image
julie01

I started 10mg Atorvastatin with methotrexate injections last August and I have had no problems, I take mine at night before bed and that seems to be the best time.

MadBunny profile image
MadBunny

I've been on both for 12 years and never had any problems. I take the statin before bed.

Annpisan profile image
Annpisan

I'm on Rosuvastatin 20 mg and Methotrexate 20 mg subcutaneously and I also have known mild-moderate ongoing liver issues. No problems in the last 2 years.

MrsSBJ profile image
MrsSBJ

me, too. Weekly 20mg Metoject for 18m and Atorvastatin 20mg daily in the evening for the last year. No problem. Cholesterol down from 8.7 to 5.2.

Best wishes.

Runrig01 profile image
Runrig01

I’m on 20mg rosuvastatin and 25mg MTX with no issues. Been taking both together for 4yrs.

I would have thought the toxicity issue would apply to the much higher doses of MTX that is used for cancer patients, where they can be on >500mg. You are monitored closely whilst taking them so any issues they can stop them.

8124 profile image
8124

HI, I have no problems with using these two medications

Mumcon profile image
Mumcon

Yes I’ve been taking these for years, without any problems

stbernhard profile image
stbernhard

Methotrexate and Atorvastatins for years. No problems!

KaysDad profile image
KaysDad

As for the above respondents, I have been taking 10mg Atorvastatin + MTX injections for some years without ill effects. In fact, statins seem to be a wonder drug from reports in the press, etc.

Briefencounter profile image
Briefencounter

Yes , I take both . Probably for the last 10 years without any problems . LFTs a little raised but not considered unusual.

Jenniet profile image
Jenniet

Ditto to all the responses so far. I have been on 80mg Atorvastatin and 20 mg MTX injections for the last 6 years with no problems. I have blood tests every 3 months. Don’t worry.

Gladjake profile image
Gladjake in reply toJenniet

thanks everyone I’m going to start statin this evening👍

zeus49 profile image
zeus49

Yes Gladjake I am on 10mgs methotrexate and Benapali 50mgs once a week. My GP put me on Avorstatins 20mgs last year. I have never been checked since to see if this is okay. I do have regular bloodtests however. I now have irregular heartbeat and nosebleeds. I do not know if these meds are the cause. Or if it is my rheumatoid getting worse. I am trying to contact my consultant or Specialist Nurse so I can discuss this. I am still waiting for them to contact me.

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