Good news about methotrexate: The suppression of your... - NRAS

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Good news about methotrexate

oldtimer2 profile image
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The suppression of your immune system and the risks of being photosensitive with methotrexate are well known. It has prompted worries that those properties might lead to a greater risk of melanoma.

A systematic review (gathering together many published articles about the risk) has concluded that any increase in risk is neglible. Ref: JAMA Dermatol doi:10.1001/jamadermatol.2022.3337

This doesn't mean that you should ignore anything that possibly looks like a melanoma, of course! - just that you don't have an increased risk.

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Shelby37 profile image
Shelby37

Many thanks for sharing this.

stbernhard profile image
stbernhard

Great, thank you for sharing this article. Apart from sun cream, common sense is a good thing to apply.

skinclinic profile image
skinclinic

Thanks …. Good to know as I’m in South America for another 2 months

I had extremely sun-sensitive skin for about a year before my RA diagnosis. Never had any issues prior to this and had always browned easily etc.

It could be possible that it is a symptom of RA itself rather than Mtx??? I am 12 years in now and my skin is fine. But it was an issue for a few years ‘around’ diagnosis.

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