Coughs and Methotrexate: Hi I had a continual... - NRAS

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Coughs and Methotrexate

s2202 profile image
13 Replies

Hi I had a continual persistent cough for a number of years while on Methotrexate and often couldn't speak without coughing.. I came off of Methotrexate because of my cough and after about 2 months I definitely felt so much better and the cough subsided. It took a number of months to go completely. At the time I had read that 1% of patients on Methotrexate developed troublesome coughs.

Hope this information helps. Wishing you better.

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s2202
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13 Replies
CagneysMum profile image
CagneysMum

That is really interesting. I have been on methotrexate just over3 years during which time I’ve developed a persistent ( although intermittent) cough that can leave me quite breathless at times. Not a major inconvenience but it must be annoying/concerning for those around me. I’ve had chest X-rays in case it’s the RA causing nodules on my lungs, but I’ve been given all clear. I’ve been told I probably have mild asthma and given an inhaler, which I don’t use because I’m not convinced it is asthma - I just think my GP ran out of ideas.

Haz58 profile image
Haz58

Hi. Are you having the lung function tests every so often? I start MTX on Sunday and had my first lung function tests yesterday, they said I’ll have to have them every few months as MTX can affect lung function.

Garnacha profile image
Garnacha in reply toHaz58

Oh didn't know this, started mtx last November & had to have a chest xray prior but that's it, unless this is something new they've introduced x

s2202 profile image
s2202 in reply toGarnacha

Hi well at the time i went to the Royal Brom hospital lung specialists in London and he told me that Rheumatologists love Methotrexate because if it's success but they really don't.

Haz58 profile image
Haz58 in reply toGarnacha

Had a chest X-ray too as well as the lung tests.

Garnacha profile image
Garnacha in reply toHaz58

How long have you been on mtx? Just wondering if its a new thing or something that I should have had done x

Haz58 profile image
Haz58 in reply toGarnacha

Only starting to take them this Sunday. x

Mumcon profile image
Mumcon

I’ve had a persistent cough for years I’ve been on Methtrexate for 11 years, I’m really bad at night I have mentioned it a few times but I feel I’m getting a deaf 🧏 ear

Haz58 profile image
Haz58

I’m quite worried now as I have a nearly constant cough anyway. My gp gave me a blue inhaler 18 months ago. Said the cough was due to allergies. If I’ve already got this cough I hope MTX doesn’t make it worse. I think I may ring the Rheumy nurse as I start taking it on Sunday.

Garnacha profile image
Garnacha in reply toHaz58

Oops sorry just saw your post above. Perhaps it is something new they've started x

Jaynes profile image
Jaynes

This is interesting. I take hydroxy and sulfasalazine and started mtx six weeks ago and also developed a cough. I wasnt offered a chest xray prior to starting it. Think maybe I should contact the rheumy nurse.

Bails67 profile image
Bails67

I have a persistent cough ( since 2014) I only took MXT for around 2 years. I am now on biologic. I have been told it was asthma, which I know it isn’t. I eventually had 2 xrays ( a few years apart ) both clear. Still coughing I got referred to respiratory clinic and had a CT scan. Consultant said thank goodness someone thought to do a ct scan. Been treated for GERD and I have very mild ILD ( something found my right lobe ) I don’t think it’s life limiting, my breathing tests are fine. I don’t think it’s abnormal with RA to have a cough 🤷‍♀️!

bienassis profile image
bienassis

I've never heard this before. But I'll certainly make a note of it. I've been taking methotrexate since 1998 without any side-effects to speak of except fatigue - but that is likely the effect of a combined biologic these days. No cough. The breathlessness sounds more worrying to me.Do you have a heart problem? But you must have been checked for that.

I do hope you get to the bottom of it. It must be caused by something. Perhaps a dry throat and mouth - not unusual, I believe, with RA.

bienassis

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