Elevated liver enzymes - methotrexate? Asthma inhalers? Overweight?

[dawkin_S]

Hi all on this grey and windy day, hope you're keeping cosy! I was wondering if anyone has been in a similar situation to me:

I had an early repeat blood test on Friday as my last one showed raised liver enzymes. Just got the results and they are raised again, so I have to book another and was told I may need to change my medication.

I currently take: 200mg Hydroxychloroquine twice a day, 20mg of methotrexate once a week, and 5mg folic acid every non-methotrexate day. The daily folic is a recent-ish addition but the other medication has been at this level for over a year. This combo has my RA under control, pretty much.

The only things that have changed recently are I've been put on asthma inhalers (brown preventer inhaler every day, blue ventolin inhaler as needed) having seemingly developed asthma post-infection back in April with possible covid. Because of this I've also been very inactive and have put on a lot of weight since April.

So, that's the pieces of the puzzle - what do you think, folks?

[MadBunny]

How long was the interval between the 2 tests? I was told to wait 4-6 weeks . It happened to me when I started on beta blockers and an anti coagulant but it was a one off. I spoke to my rheumatologist and he said that it could have been an infection or a virus. This was a year ago, pre covid days. Of course we are all different so it would be worth discussing it with your doctors to find out what might be causing it.

Wishing you well.

[dawkin_S in reply to MadBunny]

Thanks MadBunny. There were 2 weeks between the tests, at my doc's request - I guess I should double check with the doctor to see how long to wait for this one. I have had some kind of cold or similar, so could be a factor. Thanks for the best wishes .

[MadBunny in reply to dawkin_S]

Hopefully it will be just a blip.

[Nicanoo]

Hi

I've been on methotrexate for 5 years, just had 2 dodgy liver test results 4weeks apart, in sept. This month it was back to normal x

[dawkin_S in reply to Nicanoo]

Well that gives me hope that my next one might be back to normal then - thanks Nicanoo.