This is just to satisfy my own curiosity..I’ve been on methotrexate for 10yrs now and at the start of treatment I was told to take 1 folic acid tab the day after I take the methotrexate...I know that some folk take the folic acid every day except the day they take the methotrexate..does anyone know why some of us are told to take it once a week and others every day ?
Folic Acid: This is just to satisfy my own curiosity..I... - NRAS
Hi A234, I have not heard of taking folic acid only one day a week. All that I have read on it also says daily except on MTX day as it is believed to help reduce effects of MTX.
Maybe you should check with your GP and Rheumatologist.
I took MTX orally then Metoject pen injections along with daily folic acid except on MTX day but now on Leflunomide.
I take folic acid once a week also 48 hrs after methotrexate, I'm not sure why we're all given different information, I've recently moved up to 20mgs and I did ask do I need extra folic acid and my rheumatologist said no, thankfully I've no major side effects so I didn't pursue the matter any further.
I started on once a week 3 days after methotrexate day and then upped to twice a week - day 3 & 5 after MTX day. The last time my folic levels were tested I was at the top end of ‘normal’ so don’t need any more at present. Presumably if my folic/iron levels were to be low next time I’d go to 3X a week!
My first rheumatologist explained to me that MTX knocks out folate, so you need to top it up. However, at the same time there is a theory that too much folate stops MTX working effectively. Therefore she liked to start people on a small amount of folic acid, and only increase if side effects or blood tests warranted it. So I started at 1 x 5mg a week, and ended up on 3 x 5mg a week.
Each rheumy has their own theories...
And our US friends take it 7 days a week....
Hi I am on 20mg Methotrexate and initially was taking 5mg folic acid 4 days after. Due to chronic fatigue I was advised to up my dose I now take 5mg four times a week and so far so good. The meth is not working as well as they thought so I am now wondering if I am taking too much folic acid 🤔 the joys
I started off once a week but it was increased because of nausea. I was told it helps with that side effect. I now take it 6 days a week and have no nausea.
I'm in the US and my rheumy has me taking 1 mg. of folic acid every day. I think that's the norm here. I believe most people who take it only once or twice a week are probably taking a higher dosage (like a 5 mg. tablet)? So over the course of a week the dosage might work out to be about the same, or (for example) someone taking a 5 mg. tablet twice a week would be getting more than someone like me who takes 1 mg. daily.
I have been on MTX tablets since December 2015. From start told to take folic 5mg every day except the day I take the MTX. So 6 days a week. However I am taking 5mg tablets and I think some people are only prescribed 1mg. I don’t have any problems like mouth ulcers etc. And have tolerated MTX well. Strange the varied treatment. I also take Sulphasalazine twice a day, 2x 500mg each time. Plus Benepali injection 50mg once a week. No inflammation in bloods for 2 years.
Hi, I was on the once a week and the 15g MTX injection was still causing me to be sick the following day, rheumy nurse suggesting taking the 5mg folic acid the day before injection and the day afterwards, so far so good, I have often wondered why it is different for others but just do what I was told by the experts
Hello , I take it for 6 days 5mg , and miss the day I have to take methotrexate on . Rheumy Told me it’s also good for your liver whilst on mtx. And works as an energy boost , I’m waiting patiently for the energy boost lol , it’s different for different people , my liver isn’t that keen on mtx either tried it before n just didn’t agree with my body , and I’ll be told again stop and try something else 🤭
I was told by my rheumy nurse "MTX Monday's, Folic acid Friday's" but I was very nauseous so folic was increased to 3 days a week (they didn't say which 3 days! and I forgot to ask 😂). Last time I saw rheumy I was advised to split my MTX dose over 2 days and increase folic to 5 days, still get nausea though 🙄
I was started off with 0.5 mg daily(except for the methotrexate day,of course).After some months I started to get nausea,so I was told to take 1x 5 mg on the days before and after I took the MTX. This has worked perfectly for me,though I do get the occasional lip ulcer.If I do,I take a break the next time I have to take MTX,then get back on it again asap.
I was diagnosed with PsA (Psoriatic Arthritis) in March and am on once a week Methotrexate and 7 days a week 1 mg of folic acid. Into my 3 rd month on this regime, and have noticed that I am not doing as well as I was when I first went on it. Have pain and incredible fatigue. I have nights that I sleep very little and other days when I sleep for 10 hours. Pretty messed up right now.
Well; I would double check with your doc, google it and do what you are doing by asking others. I’ve been on oral tabs of the MTX for approximately 25 years taking, initially 6 tabs a week. It was increased maybe two years ago to 8 tabs a week. However, in the past year I’ve been diagnosed (late diagnosis) with three types of arthritis. Initially the MTX was for severe plague psoriasis. Presently, I have an injection of MTX equivalent to the 8 tabs. I have religiously taken a daily dose of 2-800mcg (1600 mcg) of Folic Acid for liver support. I’ve had two liver biopsies with positive results in addition to the lab work (liver panel). Rarely drink any alcohol. I hope that helps you and is reassuring. Definitely take your Folic Acid everyday! Very best to you!