Sulfasalazine

[jaqi1]

Hi everyone. What are yr thoughts on sulfasalazine please

[14bubbles]

My personal experience of sulfasalazine is mostly negative unfortunately, but this was down to my body not tolerating it well, it caused me a lot of problems with my immune system and after trying several times to build up to the maximum dose, I never actually managed it without it sending my immune system haywire. As far as I am aware, it was not a common reaction and other people are fine with it. All that being said, I believe it did improve my symptoms for the time when I was taking it, so I wish I could tolerate it!

[dembonesDAMNBONES in reply to 14bubbles]

I hear you on the immune angle.

RA, OA, Fibromyalgia and Emphysema.

It's no fun, when the Sulf knocks your immune system about.

I can't take any of the alternatives, so I'm stuck with it, however, rather than taking 500mg five times a day I take them all at once and find this a lot more tolerable, as I have one bout of nausea, then I can get on with the rest of my day and my Rheumy and GP are happy with this arrangement.

[Fighting4me_17 in reply to 14bubbles]

Really saddened for gou

[wishbone]

Sulfa was my very first med. Not on it for long though as I soon developed what looked like an insignificant rash but had to come off it.

[Mmrr]

Sulpha initially helped me, but I developed an allergy to the salicylic acid component and had to stop taking it.

[Sheenadon594]

I was diagnosed with RA in 2004 & given sulphasalazine. I had no problems at all & eventually went into remission & was discharged. Unfortunately after 6/7 years it has reared its ugly head again & I,ve just started the process all over again. It worked for me last time & am confident it will do the same again.

[mccaffs2014]

I have been on Salazopyrin for over two years. I had no serious side effects,dry skin, infected nasal tissue,yellow wee. Unfortunately it is now ineffective and I am waiting for a new treatment

[sylvi]

I was on sulpha for years when consultant took me off that and hydroxy as he wanted me on a new drug and it had to clear my system, but there have been complications and I am still without any drugs apart from MTX and painkillers. I have to say I did very well on the drug with no side effects.xxxx

[Rafandready70]

I had it added in with MTX and hydroxychloroquine and it really helped with chronic knee pain and swelling . I’m now on Benepali though so don’t take it anymore.

[sunnyweek]

I have taken sulphasalazine for about 27 years, four tablets a day, I couldn't tolerate six a day, so reduced back to four. No known side effects in that time except yellow urine.

[Happygranny1958]

I am on sulphasalaziine and methotrexate. I also cannot tolerate six tablets a day and have reduced down to three.

[beeckey]

I felt realy unwell on it lost nearly 2 stone very quickly but i know lots of people do very well on it but my body could not tolerate it.Hope you can get results with it,

[dbestdeb]

I was on it for a couple of years and had no issues except heartburn. It helped the pain but not the fatigue. Make sure you take it during a big meal to avoid stomach upset.

[dembonesDAMNBONES in reply to dbestdeb]

I'm on Omeprazole to combat any adverse effect to the stomach and it also helps with taking Naproxen, as that, too, can tear the stomach lining.

[Uga35570]

Sorry to be negative but my stomach couldn't tolerate sulfa nor could I tolerate mxt and hydroxy tablets so now am on mxt by injection much better. Hope it all goes well for you whatever med you have in the end.

[Paulajolo]

Made me very ill. Severe rash which took 6 months to clear and referral to Dermatology. Only took 4 tablets.

2 years ago now. Worst reaction to medication I've ever had.

[Hobbits]

My current biologic isn’t completely effective so my Rheumy tried me a second time on Sulphasalazine. Like the first time, really bad nausea and constant migraines. My boss found me in the lunchroom sitting in the dark. She offered me a Motrin. Bad mistake, resulted in heart palpitations. Sulphasalazine is a no go for me. I wish I could take this drug as it’s one of the least harmful ones I hear.