MXT and mouth problems

[Dobcross1]

Hi I'm on 10ml of mxt injections as I couldn't tolerate the tablets. So far they're not working (but accept I've only had 5 doses). Anyway the specialist nurse wanted to increase methotrexate dose as I'm in a bad flare but says she can't as I'm got lesions in my mouth which are bleeding and making it difficult to eat so she wants me to swap to Sulfazalazine tabs. I am really reluctant to do this as the nausea and headaches were so bad on MXT tablets and the Sulfazalazine seem to cause the same ( and can't be injected). I thought I'd found the answer with MXT injections as I didnt have any side effects at all. So confused and have to decide before tomorrow when I go in for a steroid injection and see the nurse. Anyone experienced mouth problems with MXT which have settled down??

[Hessie5]

Hi Dobcross, I did with the mtx tablets. I am not on them anymore. Hope it all works out with your decision. Hessie

[Dobcross1 in reply to Hessie5]

Thanks Hessie. Navigating a way through the drugs is minefield isn't it. It feels like I'll never be better! They wont try me on biologics as my 'disease activity score' isn't high enough but they didnt see me trying to get out of bed this morning!😁😁

[Hessie5 in reply to Dobcross1]

No worries. Mtx caused me mouth and stomach, issues so I had to change, do insist and persist although I am still to find a biologic that works. I was better on the mtx despite the issues I mention! We shall get there 😌

[Dobcross1 in reply to Hessie5]

Hope so! 😁

[oldtimer]

I had enormous ulcerated areas in my mouth with methotrexate as well as diarrhoea and vomiting. It didn't seem to like my gut at all! I lowered the dose on the injections, took the folic acid six days a week, etc, but eventually gave up on the methotrexate.

[Dobcross1 in reply to oldtimer]

Thanks for reply. Think I might have to give up too!

[Simba1992]

Oilpulling might be of help. It's soothing and keeps away bacteria. For me even though not on MTX great for gum health. Helped with my dry mouth and issues caused with this. Supplementing with gelatin powder is very good for all skin problems, as is vit. A. Good luck. Simba

drjockers.com/benefits-oil-...

[Dobcross1]

Thanks Simba I'll look at that

[Simba1992]

This might also interest you. Written by a doctor with much experience of how to manage mtx toxity.

rheumnow.com/content/dsb-ma...

[Dobcross1]

Thanks Simba that was really interesting. I also suddenly realised that the nurse only mentioned Sulfazalazine but am going to ask about hydroxychloroquinine or other DMARDS. Otherwise its mxt and vitamin A thank you.