Weight loss : I am taking 200mg Hydroxychloroquine... - NRAS

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Weight loss

Floralqueens profile image
12 Replies

I am taking 200mg Hydroxychloroquine daily, 20mg Methotrexate weekly, 5mg Folic Acid daily except MTX day. Does anyone have an answer as to why I am losing weight without reducing my calorie intake. I am currently experiencing a flare up and have had a 120mg Depo-Medrone injection. Do any of you have an explanation or experience of this? I don’t have any excess weight to lose.

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Floralqueens profile image
Floralqueens
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12 Replies
sylvi profile image
sylvi

I wish when i was on that combination i could have lost weight. I don't have an anawer for you have you contacted your gp or rheumy to ask them why your losing weight. Hugs.xxx

Floralqueens profile image
Floralqueens in reply to sylvi

Thank you for your reply, I’ll chat with my Rheumy nurse next week.

Mimi21 profile image
Mimi21

A couple of years ago I had a huge flare and my methotrexate was increased to 25mg . I was also taking hydroxychloroquine and I had my knees drained and steroid injections in them. I lost about a stone and a half in a short space of time but had no appetite and couldn’t eat whatever was put in front of me. I assumed at the time it was because I was in so much pain and very down plus leading up to that I was busy moving house and other things. On reflection it may have been the high dose of methotrexate. I am now on biologics with 15mg methotrexate, no longer take hydroxcychloroquine and have been very well thankfully for quite some time. Unfortunately I did put the weight back on but l am now regularly exercising at the gym a few times a week and regained and increased muscle tone which is supporting my knees which were badly damaged and will need replacing. Good luck!

Floralqueens profile image
Floralqueens in reply to Mimi21

Thank you x

Stynk profile image
Stynk

Hi. I have a similar issue when I flare. Rheumy just says it’s disease activity and to try and eat more and eat higher calorie items.

Floralqueens profile image
Floralqueens in reply to Stynk

Thank you, I did wonder if the body was burning more calories in trying to fight the inflammation and the disease.

Tillie20 profile image
Tillie20

Hi I am in the same medication I wish I could lose weight I have to exercise 4 days a week just to stay as I am but I am lucky because I can do some exercise I would get checked out if you are losing too much x

Floralqueens profile image
Floralqueens in reply to Tillie20

Thank you fir your response.

Joy_1 profile image
Joy_1

I you sure you are not reducing your calorie intake even just a little bit each week?

I take my MTX on a Wed night, I find I eat very little most of Thu. I have no appetite thanks to the MTX on that day.

Floralqueens profile image
Floralqueens in reply to Joy_1

Thank you, I’ll try and keep a closer check on my calorie intake.

oldtimer profile image
oldtimer

You should ask your medical team.

Unexplained weight loss needs to be monitored and investigated if it continues.

Floralqueens profile image
Floralqueens in reply to oldtimer

Thank you. I’ll speak to the Rheumy Nurse next week at my appointment.

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