How long do steroid injections last?: Had a steroid... - NRAS


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How long do steroid injections last?

helzbelz2 profile image
27 Replies

Had a steroid injection after about 48 hours it really kicked in. For the first time in 18 months my knees and elbows stopped hurting and my fingers were less sore. I felt really well and the nausea I get a lot also went. Family were saying I was back to normal personality wise.

It lasted five days. On Saturday I woke up unable to move again. Out of the blue all the pain is back in my knees and elbows and fingers and is worse than ever.

Can it really be over that quick? :(

27 Replies
hawker955 profile image

The depot injections like Depomedrone should last about 6 weeks or so.

Neonkittie17 profile image

Yes it is short lived for me usually between 7-14 days at the very most. If you have a joint injected when they are swollen etc then those intra-joint ones last months usually. I had my knee done in mid August and it's still doing very well. They last about six months for me. Sorry you have gone back to hurting.

girli1111 profile image

I got about three weeks last time - felt like a miracle!

pip12 profile image

Mine lasted about 4/5 weeks and I too thought it was a miracle cure. Had another couple which also worked very well. Just when I thought my problems where over, was told I couldn’t have anymore as I have osteoporosis and carnt have anymore steroid jabs as it tends to make the bones thinner. Back to the drawing board 😲😲😲

helzbelz2 profile image

When I was first diagnosed with sero-positive RA they gave me two depo injections and neither worked. My diagnosis has now been changed to psoriatic arthritis probably and it lasted 5 days. The consultant said if I showed an improvement I should go back on dmards.

woodstar1 profile image

I might be a bit odd but for me the depo only lasts, literally hour's. I can feel it working but is gone, just like that. For me it simply doesn't last the day, sorry.

helzbelz2 profile image

Makes me feel a bit better with my five days!

Eiram50 profile image

I’m 7-10 days. I’m sorry you’ve had little relief x

Nettac profile image

Lasts a couple weeks for me, and doesn't get rid of all the pain. Never lasts as longs as it says on the tin for me. Useful for a breathing space though.

beeckey profile image

When given into the hip they never work for me but given into the joints i get a few weeks from them.

Downtime profile image

I’ve found they last 6-8 weeks for me then I slowly start to feel tired and sore.

helixhelix profile image

Oh dear, I feel horribly guilty as I've had some that have lasted 6 weeks.... I guess it can also depend on how extreme your inflammation is and what dose they give you of steroids?

AgedCrone profile image
AgedCrone in reply to helixhelix

I feel even guiltier/luckier...a 120mg Depomedrone injected in my thigh used to calm all my painful joints & last 10/12 weeks -however another type of steroid injected into my shoulder had no effect at all...except the discomfort of the actual injection.

I'm sure a lot does depend on who does the injection.

Downtime profile image
Downtime in reply to AgedCrone

I agree. My bilateral hip bursitis seems to have been cured with steroid injections given over 18 months by my rheumatologist himself. He takes time to place the injections and they were quite large doses. They were for the hips but helped everywhere else. Previously there were times when i couldn’t walk at all because of the pain.

dwsurquhart profile image

Mine woukd depend on who did the injection. My GP did the first set and itnlasted maybe 30 hours, first rheumy lasted approx a week. New rheumy and way more experienced at injections of steroids lasted 3 weeks. Tells me that it is the location within the joint where the steroid is injected makes all the difference.

Mine took effect almost immediately

I would suggest shopping around for a very experienced almost retired rheumatologist to do your injection. They will get the correct spot and get you more relief.


JeffG profile image

Yes, sounds about par fot the course. Be careful. Steroids work, but you will gain weight, BP will increase, and you will be at risk for illness.

AgedCrone profile image
AgedCrone in reply to JeffG

Those side effects depend on the individual.....if you mean Prednisolone tablets I do understand that is the case...I only took that for a week & had to stop due to side effects.

But I had Depomedrone injections in my thigh to control all my joints on & off for 16 years & I didn't gain any weight, my BP didn't alter, & my general health stayed the same.

It's like Dmards, some people get great results & live comfortably for years, whilst others have no success with them at all.

JeffG profile image
JeffG in reply to AgedCrone

Good point. My side effects are from prednisone tablets. Injections did nothing for me.

AgedCrone profile image

I was exactly the reverse....Depo was the magic bullet...Pred sent me loopy!

Lizard28 profile image

Mine lasted about 3/4 weeks but took a few days to kick in, got it to try and make me feel better before I went on holiday, they don't have the same result as Prednisolone tabs, but I didn't want to go back on them, been on them too long.

Matilda_1922 profile image

I was told steroid will last 3 months it for me about 6 weeks

Roseposie123 profile image

When do the Prednisolone tablets start working ? I have just taken my second dose I feel so ill this is my first really bad flare for a while I am just sitting here I can’t do any thing.

Liberty43 profile image

Mine lasted 3 months. Just wearing off now. Sorry you did not have a similar experience.

Moleymum profile image
Moleymum in reply to Liberty43

Same here

Jackadoodle profile image

I had a steroid injection in my left ankle over 12 months ago, it was administered by my Rumy consultant under the guidance of a radiologist who was able to pinpoint the exact area, I am still free from pain in that area, I am going for another injection shortly for Policeman’s heel also to be guided by radiology, maybe the radiology is something new I am not sure but it is better than having injections on a guess basis by the GP.

merryl1943 profile image
merryl1943 in reply to Jackadoodle

Love this idea.

helzbelz2 profile image

Mine was just the big standard one in the bottom. Don’t seem to last

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