Hello New to the site and found it by looking up does Methotrexate cause itchy rashes. Let me tell a little about my self, I have Alopecia universalis another autoimmune condition like RA I've had it for 32 years, I've had RA for over 2 year now, and among all the meds I take Vitamin D, folic acid, methotrexate and hydroxychloroquine. I went to the dermatologist because i was getting these rash/boils/bites some big, some round, and hard, some that would ooze a substance, and all of them incredibly itchy all over my body head to toe, I was thinking spiders, fleas, very hot summer in California this year. The doc said for me to stop saying fleas, and definitely not spiders, as he said there only two that bite in California and the chances that it was those was slim to none, he did two biopsy's on arm and neck, when i returned he tried to say it was some form of acne, which I found hard to swallow, all of a sudden, i have never had acne my whole life and I'm 52. he told me to photograph them and do a diary well he left that position and went to Washington to become a politician, and they have no derm at location now, my GP doesn't know what to do as he needs to get a referral for me to go to another Derm at the moment all open slots are full. So I'm at a stand still, the pain of my RA is getting so bad, that I couldn't even get out of bed the other day, but the constant pop up of these skin bumps/rashes/bites/hives are driving me out of my mind, I can't sleep, i cant' stop that feeling of wanting to rip my skin apart and the money I'm spending on itch relief is almost the price of the meds, and may I add none seem to work at all. So I do't know what to do, or what is the worst of two evils. I would appreciate any advice, as I'm really feeling I can't deal with this.