Hi, I have always not done well on MTX but apparently it works well for me. The nausea has possibly even got worse this summer, could also be the heat wave and smoke from all the fire, but it has been verybad. My GP has been trying and we have tried Maxiran for nausea it helps but makes me super jittery. Then Donparadone no help at all. Now it is Nasinan but I still have to try it and see but what I read so far is it is more of a antipsychotic and seditive then a analgesic. Anyone try it before??