Hi all - I am on my sixth week of methotrexate 10mg. Felt absolutely fine for the first 2 weeks, but every week after that brought greater nausea. Feeling very sick now. It seems that most people have a decrease in nausea the longer they take mtx, or as they get accustomed to it? I'm taking 5mg folic acid on the other 6 days per week, and drinking loads of water.
Sorry if this seems like a trivial question, but here in South Africa they don't monitor us as closely as they do in the UK - after the initial pre-medication blood test, the next test is only scheduled for mid-July, after 9 rounds of mtx. Just worried, and needing reassurance that others have had similar nausea increase without adverse liver effects. Thanks in advance!