I am on leflunomide. And come of sulfasasazine and have noticed a difference already, as I don't. Feel as tired as I was. I don't. Even have to have a sleep in the afternoon anymore. The down side is, headaches, very painful mouth as in raw gums and swollen gums, I do suffer from gum disease but this seems to make it worse. Had a bit of diarrhoea very suddenly a few days ago and last week. But that seems to have moved on for now. It's just so nice not to feel fatigued.
Thanks for listening.
Carol x