Injectable methotrexate versus oral

[Laineymacd]

Does the injectable methotrexate work better then oral ???

Hope so as I started it today

[popsmith1874]

I've been on it for 3 years started off on tablets but kept making me sick

[helixhelix]

You get more of it, as none 'wasted' in your digestive system. So the same dose should be more effective, but as with everything RA it depends!

[JEM95 in reply to helixhelix]

I get less severe side effects with injections - something I am hugely grateful for.

[Diddydriver]

I have been on the injections now for almost a year and I find that it is so much better than tablets, much less side effects, and easy to do. Mine are pre filled syringes. Hope you get on alright. X

[Tillie20]

Hi I have been on mtx injection for about 7months and feel so much better the tablets made me feel very nauseous hope you feel better when you start X

[LizzieR]

They also make me less sick. Hope they work well for you x

[Kate23]

Hi, I only started on the MTX injections 5 weeks ago....easy to do, doesn't sting and NO nausea at all, just a headache on the day ...obviously too early to show any benefits but fingers crossed.Good luck.

Ps I was told to get a letter from Dr if I went abroad and had to take the syringe with me.

[nomoreheels]

Generally changing from tablets to injections is a positive move as the injection goes straight into the blood steam not the gastro system as tablets do. As such less of the dose is lost so often a lower dose than in tablets can be effective. I was on tablets for a year & when I needed an increase in dose from 15mg to 20mg my liver had a benny so I went onto injections & I was able to go back to 15mg with positive results. I've been on them 7 years, currently on 17.5mg.

I hope you find them better too.

[Hidden]

I like the injections better, no more upset tummy! Your body absorbs more mtx because it i goes directly into your blood stream.

All the best to you

Sue

[Laineymacd]

I am doin much better on the injections ! Tablets upset my stomach