Injectable methotrexate versus oral : Does the... - NRAS

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Injectable methotrexate versus oral

Laineymacd profile image
10 Replies

Does the injectable methotrexate work better then oral ???

Hope so as I started it today

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Laineymacd
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10 Replies
popsmith1874 profile image
popsmith1874

I've been on it for 3 years started off on tablets but kept making me sick

helixhelix profile image
helixhelix

You get more of it, as none 'wasted' in your digestive system. So the same dose should be more effective, but as with everything RA it depends!

JEM95 profile image
JEM95 in reply to helixhelix

I get less severe side effects with injections - something I am hugely grateful for.

Diddydriver profile image
Diddydriver

I have been on the injections now for almost a year and I find that it is so much better than tablets, much less side effects, and easy to do. Mine are pre filled syringes. Hope you get on alright. X

Tillie20 profile image
Tillie20

Hi I have been on mtx injection for about 7months and feel so much better the tablets made me feel very nauseous hope you feel better when you start X

LizzieR profile image
LizzieR

They also make me less sick. Hope they work well for you x

Kate23 profile image
Kate23

Hi, I only started on the MTX injections 5 weeks ago....easy to do, doesn't sting and NO nausea at all, just a headache on the day ...obviously too early to show any benefits but fingers crossed.Good luck.

Ps I was told to get a letter from Dr if I went abroad and had to take the syringe with me.

nomoreheels profile image
nomoreheels

Generally changing from tablets to injections is a positive move as the injection goes straight into the blood steam not the gastro system as tablets do. As such less of the dose is lost so often a lower dose than in tablets can be effective. I was on tablets for a year & when I needed an increase in dose from 15mg to 20mg my liver had a benny so I went onto injections & I was able to go back to 15mg with positive results. I've been on them 7 years, currently on 17.5mg.

I hope you find them better too.

I like the injections better, no more upset tummy! Your body absorbs more mtx because it i goes directly into your blood stream.

All the best to you

Sue

Laineymacd profile image
Laineymacd

I am doin much better on the injections ! Tablets upset my stomach

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