I've been sitting here staring at these 3 tiny methotrexate pills for hours trying to get my nerve up to take them.. I take diclofenac potassium 50mg 3 times a day and everything I have read said to not take methotrexate and diclofenac together.. I want so desperately to feel better but I'm afraid to stop taking the diclofenac... All the negative things I have read about methotrexate have me absolutely scared to death. Hair loss, foggy head, upset stomach, etc... Doc wants me eventually to take 8 pills a week. How am I gonna get to 8 if I can't even take 3?? I need some reassurance about NSAIDS and methotrexate also any positive feedback would be much appreciated!