Sulfasalazine

[Megan2005]

Hi. Just been prescribed  Sulfasalazine along with leflunomide which I have been taking for the past 3 years, in so much pain , just hope this works. Anyone out there know of any side affects. Thankyou. 

[gwynedd]

Hi Megan, 

I've been on sulfasalazine for about 4 months, had a bit of a bad tummy for the first week or so but have been fine since. Except for bright orange pee! I hope it works for you and you get some relief from your pain. 

[Megan2005]

Thankyou for your reply. I'm feeling ver nauseous at the moment hope it goes soon.

[Crusee]

Hello,

Yep same with me,orange wee and also significant hair loss.

However I was also on mtx jabs at the same time so don't know if they reacted with one another or whether it was just the sulfasalazine.I was on 6 tabs a day and even when I was cut down to 3 per day it made no difference to the hair loss.

Hope you get on with them ok and that they work for you.

Crusee

XX

[sylvi]

I am on sulpha and i haven't had any side effects.xxxx

[Hidden]

Hi I last take sulfasalazine 500mg tablets 4 a day, with no side effects at all, it's wonderful for me, I changed from mtx to sulfasalazine as couldn't tolerate mtx, and been totally fine. Apart from the yellow urine, but it isn't a problem and is safe to see this. Good luck, hope you tolerate.

Lady B 😊x

[beckywebb04]

I had a horrendous sore throat, was in tears with it and felt like I'd swallowed razor blades then drank acid. Couldn't eat or swallow. Apparently that's rare though because I had to figure it was caused by the sulfasalazine myself

[nomoreheels]

I've also just this last week started sulfasalazine, just the one tablet this week & not had any side effects. It's been added to MTX due to disease activity in my feet. I always read the patient information leaflet when I start something new but tend not think about what I may or may not expect otherwise I think you just wait for them to happen. Just my coping mechanism I suppose. No really answering your question but I'm sure someone will be along who's been on it some time & pass on any side effects they've experienced.

[moomie]

I ha e been on it for nearly 6 years, initially had a brilliant response. I was able to come off long term steroids.

Now take 6 a day plus hydroxy and mtx.

Only side effect I get is Sun sensitivity. I am fair skinned though. Just remember to apply high 

[moomie]

P.s tablet playing up and cut out and posted.

Apply a high factor cream even in winter when the Sun is out.

Hope it works well for you. Good luck Moomie

[beeckey]

just made me feel ill no appetite hope you do better on it

[wannabhealthy]

Been taking 6 tabs SULPHA per day for last 16 months + MTX + HYDROXY.  Few teething probs for first 4 weeks but fine now.  Good Luck!

[Vixen2]

i know this post’s 7yrs old!!! But i’ve had RA for 31yrs. (Since i was 21). I was first put on Sulphasalazine. (About 4 a day. About 3 a day of Indocide, steroids & co codymol & co dydramol). I felt very ill on them. Felt sick constantly. Had to eat a lot of mints to ease the sickness. Then 1 day i couldn’t recognise my brother in law. I was totally confused. Couldn’t read or write. I was a zombie. Felt so ill. My consultant lowered the doses the next day. I was fine. Then the nausea just seemed to vanish. It just shows you how strong these drugs are.

Now i have an infusion of Infliximab every 6 weeks. I’ve been on this drug for 20yrs. Thank God for the NHS. I know this post was 7yrs ago. So i’m not expecting a reply!