I have been on a low dose of methotrexate for 6 weeks now, my rheumatologist will review this in march. Does anyone know how long it takes to work? I am feeling really low at the moment, I'm so fed up of waking up stiff and in pain that I cry every morning. I have managed to cope with pain over the years with pain relief meds, but recently I have had enough. I have been on long term sick for 5 months now and cant honestly see me going back. Everthing just feels too much at the moment, I am 57 and live alone. I have family close by and young grandkids, but still feel lonely and isolated. I am finding myself withdrawing from my family and friends, making excuses or telling white lies to avoid going out.
i am taking anti depressants, but I really need the Methotrexate to work.