Good morning all. This is my first post so please excuse me if I get it wrong. I was diagnosed with RA approximately 2 years ago. I was put on methotrexate a year ago but taken off of it because of my liver. Selfosalazine was next but taken off of that as well. Know I'm on leflunomide. I'm having loads of side effects so I've been told to take a week off of it. It was really bad last week when depression set in and I felt suicidal for a couple of days. Blood tests are all in range apparently. Really tired, kidney pain, bad stomach, bruise really easily and aching joints. Has anyone experienced this and if you have what did you do?