Been on Indometacin, salphaselazin and omneprazole ( excuse spelling) for a 18 months now and consultant has just put me on methotrexate as no real pain relief with current mix. Confused over whether I should continue with just Metho and ditch the rest or what? Got cough cannot shift, had chest X-Ray, all OK? And radioactive dye bone scan which proved inconclusive. All blood tests prove negative, Liver OK buy only just - they scratching head as to what my chronic unstoppable pain in wrists and hands is or what to do to ease the pain? Steroid injections did nothing. All seemed to start 4 years ago when grapefruit size growth on ovary and another in womb size of 16 week pregnancy required total hysterectomy then 2 years ago a bad tooth infection caused pancreas to pack up and become insulin dependent at 53 years young, feel like I'm falling apart with medics clueless other than to try some other drug to see what that might do!