I have been reading the internet for symptoms of seronegative arthritis and it doesn't fit with what I have. I have no joint swelling and no stiffness in any particular joint. My stiffness comes and goes, mainly in my neck. I have really bad toothe ache pains i n my hands which start when I wake up. They ease off through the day. Some days I can't grip things because my wrists hurt too much but that improves with the day. I take prednislone for pmr but I have been told these pains I get are not that. Still as I lower my steroids my ESR goes up. My Dr didn't know if you get a raised ESR with seronegative arthritis does anyone on here?. I take Hydroychloroquine and have been taking it for over three months, I'm not sure it is working. I really don't want to start Methotrexate when I have my doubts about my diagnosis.Does anyone have similar symptoms and what were you diagnosed with?