I think this was mentioned in a post just recently and it has come back to me this week as a possibility for me.
I have this disease now for nearly 4 years. I am sero negative and can't take MTX. I qualified for Bios and was started on Humira.........long story short......after three Bios that for different reasons weren't for me I was put on Abatacept two years ago in November just passed.
This drug, as all the Bio's I was put on, was a wonder drug for me. I was as far as Iwas concerned in full medically induced remission. I was vertually pain free except for the parts of me that have some form of deformaty. This continued up until early summer of this year when I had a flare and experienced 'lock jaw' due to RD in both side of my jaw although at the time I only had pain and deformaty in the left side.
I got a steroid injection for the flare and and it eventually eased, as they do. However I never really went back to the level of pain relief that I had previous to the flare.
Gradually almost all of my 'old' pain has returned and now unfortunatly I now have 'new pain'.....the disease has started to spread again. This is awful for me as I was sure that this drug was what I delieved to be my future, a pain free future.
On Sunday passed my son and I helf a surprise 90th birthday party for my Father. Attending was a cousin and he daughter, who happens to be a Chemist. We got talking and it turns out she makes up my prescription for Abatacept at the local hospital. When I told her about what was happening to me she asked me if I was told that these drugs tend to only have an effectivness for a few years? I wasn't! I was told what everyone is told, they may or may not work, they can take a long time befor they are effective etc, etc. Never at any time was I told that their effectiveness tends to decrease within a few years.
I have a 1st class Rheumy team who have given me the very best of care and attention. I will be attending an emergency appointment today and I will be asking questions. Abatacept is the last drug available to me......for now, I was told that. If I am at the end of the road with regards to thee most effective medication I can tolerate I really want to know about it.
I would really like to know if anyone else has had this experience with Bio's and if your medicial team made it know that they cease to work after a few years.