Sulphasalazine : Hi all, hope your all as well as can... - NRAS

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Sulphasalazine

Titchyj profile image
8 Replies

Hi all, hope your all as well as can be. I have been taking Sulphasalazine now for 8 weeks, and for the last 4 weeks I have been suffering with acid reflux, waking me up at night. I was wondering if anyone else have suffered with this whilst taking Sulpasalazine ? I already take 40mg per day of omeprazol for reflux and hiatus hernia.

Jan

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Titchyj
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8 Replies
allanah profile image
allanah

The docs increased my omeprazole to two a day and that helped xx

Titchyj profile image
Titchyj in reply toallanah

Thanks Allanah, I take 2 a day, 20mg x 2 daily, which has been fine for many years until I started Sulphasalazine, could there be an interaction between the 2?

Jan

allanah profile image
allanah in reply toTitchyj

In my case the sulpha does cause indigestion d diarrhoea initially but the increSed tablets helped. Maybe go have a chat with the gp for another tummy remedy ?

nellysgran profile image
nellysgran

Hi I take 2 x 20mg Omeprazole in the morning then before I go to bed take 2 x 150mg R.anitidine for my reflux which is really bad if I don't have them. Ask your GP

Titchyj profile image
Titchyj

Thanks both, I am seeing GP this morning, so will ask him about this. I too get diarrhoea occasionally with the Sulphasalazine, but not as bad as when taking MTX. My hands are really swollen and painful. Hoping for a steroid injection today.

Jan

dbestdeb profile image
dbestdeb

I've been on sulfasalazine for 2 yrs and have had the problem off and on. My rheumatologist told me to take the drug in the middle of a meal and my gastroenterologist has me on an acid reducer. As long as I follow the instructions and take the acid reducer, I don't have the problem.

shazmill profile image
shazmill

i developed this reflux from taking Methatrexate. I have just started taking 500 mg Sulphasalazine. How do you feel on this drug? Have you experienced the side affect mentioned by others?

Fireglow profile image
Fireglow in reply toshazmill

Itching every night slight nausa now gone.into 2 weeks now

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