Hi everyone you may remember that I wrote a few days ago about probs I have been having in the bottom department. Went for my appointment at the RA clinic on Thursday and the nurse said they didn't believe the methotrexate is causing lose bowels. Anyway she told me to drop down to 4 methotrexate on a Friday instead of 8. She also advised me to get a sample tested by my gp, I wonder what any of you lovely peeps think about all this. Thank you all.