I have been having persistent flare-ups after 2 years of weekly self-injected 25mg of Methotrexate and daily Hydroxycholoroquine tablets. I used to take steroid tablets to assist me during these flare ups (usually left knee and wrists) but they have now lost their impact and in-joint steroidal injections only last for a very short period- the latest flare up being only 2 days after an in-joint steroid injection. I am looking to push for biological drug treatment as I am only 21 and feel that I should have gained much better control on this disease after 2.5 years. I am wondering if anyone has suffered side effects, severe or otherwise and particularly young women, from Golimumab treatment and whether it will affect my fertility later in life. Any knowledge on this drug would be most helpful.