Dobutamine injection for heart test

[Snoopy53]

I recently had an IV with drug Dobutamine. My GFR was at 51 and Creatinine was at 101. Bloodwork was taken the next day to check my A1C and I was shocked to find that my GFR went down to 34 and Creatinine jumped to 142. Anyone know if the Dobutamine was cause? I'm very concerned.

[CKDnomore3953]

Thank you for posting this question. My doctor also wants me to do a cardiac stress test with Dobutamine - but I am concerned about the possible effects on my kidneys (eGFR 49). I hope you get some helpful responses.

It might be a temporary effect and your eGFR will return to your pre Dobutamine level in a few weeks. I hope that is the case for you.

[Snoopy53 in reply to CKDnomore3953]

I am hoping it will as well. I also had carbon dioxide contrast IV along with Dobutamine. It is my understanding that that type of contrast doesn't affect kidneys, unlike iodine based contrast.

[CKDnomore3953 in reply to Snoopy53]

I had not previously heard that CO2 could be used as a contrast agent in angiography. I looked it up on PubMed and ScienceDirect and there are quite a few research articles about it.

Healthunlocked is such a great forum for learning more about our health issues.

[Snoopy53 in reply to CKDnomore3953]

Forgive me. I was mistaken. They used CEUS as contrast agent with dobutamine in the ultrasound for my heart

[Marvin8 in reply to CKDnomore3953]

I would ask the doctor if he has a good reason to give you dobutamine instead of putting you on a treadmill. My doctor prescribed it as a matter of course, but I blew a gasket since he could easily see that I could handle a stress test. He changed it no dobutamine and apologized.

[CKDnomore3953 in reply to Marvin8]

Hi Marvin, My doctor recommended the dobutamine test because I have bone on bone arthritis in my right knee and I cannot run on that knee long enough to get my heart rate up to the level they need to see. I also have CKD which makes me wary of any test that requires contrast dye - which is frequently used during an exercise stress test. I told my doctor that I could do an exercise stress test on a bicycle but my Medicare advantage program does not have any bicycle stress test and I couldn’t find a bicycle stress test offered anywhere in the large city that I live in.

[Marvin8 in reply to CKDnomore3953]

I understand completely. From what I've read, the dobutamine shouldn't harm your kidneys and I wouldn't hesitate to use it if I were in your shoes. I also feel the same as you about contrast dyes.

[David7]

Hello, Creatinine can't be 101. Normal levels for a male are 0.7 to 1.2All the best.

[Wescott in reply to David7]

Creatinine is not reported that way in Canada. My creatinine is around 265.

[Snoopy53 in reply to David7]

I live in Canada and the range for normal Creatinine is between 50-100 umol/L. I was at 101

[David7]

Thank you for clarifying, Snoopy . Best regards,

David