Interleukin-11 Inhibitor (potential for kidney regeneration in CKD)

[Pontios]

Following on from the recent news in February 2023 that Duke NUS and NHCS scientists found that blocking an immune regulating protein Interleukin-11 (IL-11) can stop and even reverse kidney damage caused by acute and chronic kidney disease in mouse models Boehringer Ingelheim (Pharma company) have announced they are starting clinical development on an IL-11 Inhibitor with a Phase 1 study.

This is only shown so far in mouse models. But if this proves successful in clinical development it appears we could regenerate already damaged kidneys to some degree.

boehringer-ingelheim.com/me...

eurekalert.org/news-release...

[KidneyCoach NKF Ambassador]

Perhaps, but we likely wouldn't see benefits for at least a decade. IMHO

[Blackknight1989 in reply to KidneyCoach]

Absolutely correct Coach if by then…the breakthroughs are tremendous but the process of implanting anything resembling a God-Crafted (my personal belief doesn’t have to be yours) kidney is currently beyond the working knowledge or at least the conceptual thinking of current research. Don’t misunderstand my point, I am grateful for the progress as the younger generations my kids age will most likely benefit from the leaps being made now but I do t believe that’s in the cards for us!