Duke-NUS and NHCS scientists first in the world to regenerate diseased kidney

[ling]

eurekalert.org/news-release...

Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease

nature.com/articles/s41467-...

Researchers have found a way to enable damaged kidneys to regenerate!

Best news yet this year.

Human trials start 2023. Pray God the trials yield positive results.

[ashok5085]

Wow! Atleast something positive for us.

[ling in reply to ashok5085]

So true

[Dana66CKD]

Wow! I hope this is coming soon for many. It would be a real miracle.

[wayner43]

it would be a blessing it could end up helping millons

[Blackknight1989]

Careful, if you read the full study text kidney cell “regeneration” is only indicated for AKI not CKD. Specifically the Discussion section of the study says only this regarding CKD:

 In CKD, anti-IL11 was associated with TEC proliferation, restoration of kidney parenchymal mass and reversal of renal failure. Importantly, unlike anti-TGFβ, anti-IL11 therapy reduces renal inflammation/tubule damage and target safety signals in humans and mice deleted for IL11RA or IL11 are encouraging35. Our studies suggest potential therapeutic opportunities for anti-IL11 in acute and chronic kidney diseases. In fact, nearly the entire article is about AKI CKD is mentioned only in the very last section and the discussion.

Link:

nature.com/articles/s41467-...

I don’t mean to rain on anybody’s parade just trying to bring some additional information that might clarify this subject. Some additional information on research into potential kidney cell regeneration:

frontiersin.org/articles/10...

academic.oup.com/stcltm/art...

stemcellres.biomedcentral.c...

Research into stem cells is promising but no clinical trials have begun to test any potential regenerative therapies in humans. Still a need for funding and for more medical studies. Maybe one day but the research into the artificial kidney is in phase 1 clinical trials. My hope is those will progress smoothly and the artificial kidney could be available in 3/5 years. Links:

kidneyx.org/prize-competiti...

pharmacy.ucsf.edu/news/2021...

asn-online.org/about/press/...

Or xenotransplantation:

healio.com/news/nephrology/...

pubmed.ncbi.nlm.nih.gov/355...

Please understand this is not a personal attack on the original individual who posted the news or a need to prove something incorrect. Just an attempt to provide perspective and additional information in the hope it may help someone. I appreciate the link from the OP and the new information. Finally, may all of you be successful in your journey towards your best health!

[ling in reply to Blackknight1989]

Thank you very very much!

[Blackknight1989]

I sure hope I didn’t offend you with my post. That was not my intention at all. If I did I apologize. I appreciate your reply and it is my pleasure to add additional information. As always, my very best wishes in your quest for your best health!

[ling in reply to Blackknight1989]

Its good to know there's still the artificial kidney. Many thanks for the info

[Blackknight1989]

My pleasure. Take care!

[70Beach]

Please keep us updated!

[ling in reply to 70Beach]

Hi. Sorry, please see Blackknight1989's post above.

My mom's 88 and has quite quickly deteriorated to Stage 3A. Like you, i am very vexed by the diet problem as well : (