Canagliflozin featured as a new treatment - Kidney Disease

Kidney Disease

11,112 members4,803 posts

Canagliflozin featured as a new treatment

Trill profile image
5 Replies

Today's 'i' newspaper reported an article in The New England Journal of Medicine double-blind tests, the result showing it reduced kidney failure by a third, and cardiovascular events by 20%. As it is already a drug in use to treat Type 2 diabetes, it is currently readily available. Sounds good news The Professor of metabolic metabolism at Glasgow University described it as having 'the potential to revolutionise treatment of people with diabetes and kidney disease'. This is just to inform you of a new development not to promote it or agree with it. Just FOI.

Written by
Trill profile image
Trill
To view profiles and participate in discussions please or .
Read more about...
5 Replies

The link to the full article mentioned by the above poster is below. Read and draw your own conclusions. Right now I believe it's too soon to make any grand announcement. Of course that's just my opinion and I could be wrong.

nejm.org/doi/full/10.1056/N...

SN23 profile image
SN23

Yes I read this too👍👍🤞google.com/amp/s/amp.cnn.co...

Bassetmommer profile image
BassetmommerNKF Ambassador

I got so excited when I first looked into this drug. But when I went to the website for the drug side effects, I got dissapointed quickly. This is what it said for side effects: "Acute kidney injury. Consider temporarily discontinuing in settings of reduced oral intake or fluid losses. If acute kidney injury occurs, discontinue and promptly treat. Monitor renal function during therapy (5.4)"

So as most drugs, it is a chance you take. I also did not like the warning about amputations.

I sure wish they would spend some time figuring out a drug that would cause less harm and do more good. But then, it would make the diabetic drug manufactures furious at the money they would lose. And we know how big that lobby is!

janssenlabels.com/package-i...

Trill profile image
Trill in reply to Bassetmommer

Yes I saw that online but strangely the article quoted says 'There was also no increased risk of major side effects'.

htpi1543 profile image
htpi1543

This is the kind of information we all need.

You may also like...

SGLT2 new treatment for CDK; anyone on them?

inhibitors, many patients with non-diabetic kidney disease show progressive kidney function loss,...

New eGFR calculation Coming.

Just received an email from the NKF announcing a new method for calculating eGFR. See link below...

New diagnosis at ckd 3a

the conversation. However, I am concerned as my kidney function has declined 10 in the last five...

New Treatment for IGA Nephropathy

I have IGA Nephropathy and am always looking for new treatment options. I recently found Tarpeyo...

UTI treatment for ckd patients

infection. It resolved but wondering if any harm to kidneys?Pretty miserable now with UTI. I'm...