Control of High Protein in Urine with dibeties

[Vivekks]

Hi.Can any one please suggest that Tarpeyo medicines is useful for high protein in urine near 1575 ppm or not.

I have study which show it also have negative effects with high blood pressure.

Please suggest as this is a type of stroide.

If not can any one know other type of safe medicine for proteinuria.

Thanks

[jodaer]

I found this on Drugs.com

Tarpeyo is a prescription medicine used to reduce levels of protein in the urine (proteinuria) in adults with a kidney disease called primary immunoglobulin A nephropathy (IgAN), who are at high risk of disease progression.

Other than that, I don't know anything about it.

[Vivekks in reply to jodaer]

Ok Thanks Jodaer

I think it is a steroid which have side effects on high blood pressure.

Can any one please suggest other medicine and side effects of this drug.

It is safe or not to be used.

[userotc]

Generally I am negative about drugs, partly because of the side effects. My mum includes cordyceps within a natural protocol of nutrition and lifestyle. Whilst we were/are concerned about her increasing proteinuria, it's significantly 10x higher via: endmemo.com/sconvert/g_lppm...

[Vivekks in reply to userotc]

Hi userotc.Thanks for details.

Yes I have 1030 mg /day protein in urine.

Its 10 time higher than normal range.

Can you please suggest any other medicine which help in control of foaming in urine.

Thanks

[userotc in reply to Vivekks]

Do you mean 10300mg/day? 1030mg = 1.03g which is low nhs.uk/Livewell/Kidneyhealt...

I cant advise on drugs as we dont use them!

[Vivekks in reply to userotc]

Hi Userotc.Yes it is 1.03gm per day. It is high in biological reference. In biological reference maximum limit is 0.15 mg per day. It is 10 times higher.

Thanks for above link.

[userotc in reply to Vivekks]

Hi Vivekks. I presume/hope you meant 150mg/dy not 0.15! Not sure what you mean re biological but this link concurs: gpnotebook.com/simplepage.c...

Mum's nephro appears happy with her 24h fig of <0.44g so presumably he is following NHS guidelines of <1g/dy (my previous link) rather than <0.15g. He would likely be OK with your 1.03gm/dy so I presume youre following other guidelines or g/l figure which is ~10x limit, as I indicated earlier?

[Vivekks in reply to userotc]

Hi Userotc.Yes it is 150 mg per day protein level is normal in 24 Hrs Urine Protein Analysis.

I have value 1030 mg per day at this time.

It is good to hear that your mom have< 0.44g .It is normal.

Can you please suggest which medicines your mom has used in treating proteinuria.

Thanks.

[userotc in reply to Vivekks]

Whilst 1030mg/dy is indeed much higher than 150, it is only fractionally above the "low" limit of 1g/dy according to my NHS link earlier so I don't think it's of great concern yet, at least according to NHS. For the same reason, I agree with you that mum's </=0.44g/dy is normal - yet it is 3x higher than the 150mg limit you prefer?

As advised, we don't use medicines but mum takes cordyceps supplements for this reason. We don't know if it alone is helping as its part of a comprehensive Nutritional Therapy protocol.

[RoxanneKidney]

The best out there are the SGLT 2 inhibitors with Lisinopril. The mistake doc make is they prescribe too high of dose. Starr small and work your way up.

[Vivekks in reply to RoxanneKidney]

Hi Roxaner.Thanks for details. I am taking Olmystron for BP management. My BP is in range 84/120.

Is there any other treatment of proteinuria treatment.

Please suggest.

[RoxanneKidney in reply to Vivekks]

Mayo doctor told me best thing was Lisinopril. They have SGLT 2 inhibitors now too but the Lisinopril seems to be working for me right now

[Vivekks in reply to RoxanneKidney]

Hi Roxanne.Thanks for details.

It seems good that Lisinopril work.

I am taking Olmystron in place of Lisinopril as my doctor suggest.

What was your protein level initially and currently after taking Lisinopril in 24 Hrs protein analysis test in urine.

[RoxanneKidney in reply to Vivekks]

Around 500

[Jimbo63]

Look up ARB for urine protein.They are Losaratan Telemasartan Valsartan they control protein urine

[Darlenia]

Diabetes and IgAn are two different diseases. Diabetes is a disease involving glucose regulation. High glucose quietly takes out the blood and filtering vessels in your kidneys so they can't remove protein so those proteins then wind up staying in your urine and blood. So, if you're a diabetic, the best "treatment" for high protein is to cut back sugar and carbs. You can lower protein in your labs with diet or medication, but the primary issue is glucose. My hubby is a T2D and his labs responded beautifully when he finally took to watching his sugars and carbs seriously. Unfortunately, he started this too late and went through kidney failure, dialysis, and transplant. Sadly, once vessels are compromised in the kidneys or elsewhere in the body, the situation can't be revered. So, yes, you can work on protein (the end result) but probably optimum to put most energy on your glucose levels (the reason). Diabetes, in my view, is a disease of the vascular system, but it can be stopped. Wishing you the very best in getting an optimal outcome for yourself. It can be done!

[Hidden]

Ask your neph about SLGT2 inhibitors since you are already on BP meds. All the best.