Hello all ,
I was first diagnosed with kidney disease in 2014, since then I have dropped from stage 2 into stage 3 and now I bounce between stages 3 and 4. I was just told that I am now pre diabetic. Has anyone heard of kidney disease causing diabetes?
Actually, it's my experience that it's the other way around. I've had diabetes for almost two decades and found out 16 months ago that I had CKD. Medically, everything I've read shows that Diabetes of either type is a leading cause of CKD, as is hypertension. I've not read anything that says it is the other way around. Having said that I'm sure there are articles that I haven't read that say it's possible. Have you asked your physician if that's possible?
I see my nephrologist in December, my GP told me that I am prediabetic, the funny thing is I’ve had kidney disease for the past four years, last year I started having hypertension, And this year I now pre-diabetic. I guess I’m just trying to figure out why and how all this is happening, and how to keep it from progressing.
If you are in the US have you been to the Kidney Smart class? You can go to the DaVita website at davita.com and look for the free, 90-minute class in your area. It's taught by a kidney professional and they can offer you solid information on that question and others.
Thank you. I will do that.
I found one article that says yes, CKD can cause diabetes. sciencedaily.com/releases/2... According to the article it is due the build up of toxins in the blood.
Being forewarned to having diabetes is a good thing. Take control by learning about a renal and diabetic diet. See if you can get a referral to see a renal dietician. It is the best way to stem off the progress of either CKD or diabetes.
Thank you
Thanks Bassetmommer for the link. I have been recently diagnosed with pre-diabetes. I am at eGFR level 3b. My eGFR has been declining slowly for years.
I checked out the link and found some interesting contradictions. Phrases like ...novel link..., ...may be responsible... are problematic. Also, no humans were involved in the testing and research performed as mentioned in this article, only mice. So, the jury is still out on the causal links of CKD triggering Diabetes. Until then I would suggest it is one less thing to worry about until conclusive evidence is found and accepted.
Well, just because I like a good discussion, what you pulled out of the article is incorrect. This is the direct copy from the article "We identified molecular mechanisms that may be responsible for increased blood glucose levels in patients with non-diabetic chronic kidney disease. Our observations in mice and in human samples show that the disease can cause secondary diabetes," said Dr. Vincent Poitout, researcher, CRCHUM Director, and principal investigator of the study." sciencedaily.com/releases/2...
So they did do human testing (see above and below) and.... with a little medical background, this makes a lot of sense. If the kidneys are not filtering correctly, there is the likelihood of glucose being built up in your systems. If the cells are not absorbing the glucose it will build up and if the kidneys are impaired they may not be able to get rid of it. Hence, diabetes.
And further in the article "Dr. Poitout's laboratory, has proven that the opposite is also true. "About half of those affected by chronic kidney disease have abnormal blood sugar levels. I wondered why. We conducted experiments in mice and found impaired insulin secretion from pancreatic beta cells, as observed in diabetes. We observed the same abnormalities in samples of pancreatic cells from patients with chronic kidney disease," explained Dr. Koppe."
We may have to disagree here because the sentences below cover the comment about a "novel mechanism" and also "further studies are required to validate these findings in humans." Their sample of humans was way too small to be taken seriously and they even suggest that further studies are needed with humans to substantiate their initial claims. They tested mice exclusively and only made observations of humans.
Personally, before I support that idea, I would want more conclusive proof and supporting data. There are no other scientific studies available that support their claims. I realize that someone must be the first in any groundbreaking discovery but until others come out in support of their finding permit me to be skeptical.
The study is important because it reveals a link and rather novel mechanism between chronic kidney disease and diabetes. "Further studies are required to validate these findings in humans. But if our observations are confirmed, it will mean that patients with non-diabetic chronic kidney disease are at risk of developing diabetes.
Thanks for the great conversation Bassestmommer. What a great way to spend an otherwise boring Saturday afternoon.
Hi, diabetes is the single biggest cause of cad
Philip
Lupus nephritis 
stopping the rapid decline in GFR
Introductions
High Uric acid 8.7 and diet
Depression?
