I started taking Tecfidera 2 weeks ago and felt very minimal side effects, slight nausea and mild headache. Last Saturday I began having explosive diarrhrea, vomiting, abdominal pain, drenching sweating and headaches, mostly in the middle of the night and early morning hours. I called Biogen and was encouraged to continue taking it until my neurologist could be reached. This being a 3 day holiday week-end, I can't reach my doctor until tomorrow. Has anyone continued Tecfidera and tolerated the side effects? How long did the side effects continue? I haven't left my house in 3 days, and took my last Tecfidera last night. I cannot function with these side effects. I lead a fairly active life style. I like to hear similar experiences and they turned out.