Jak Inhibitors for Eczema

[Nikey92]

Hi, i have recently been to a dermatologist regarding my current Eczema flare, it's having a big effect on my day to day life and I was seeking relief. I stopped using all steroids 5 years ago, withdrawal from them was painful so I am not ever using them again. The derm I saw last week was one of the better ones I have seen and he has suggested a Jak Inhibitor called Olumiant. I have done some research and it doesn't come without potential risks, just wondering if anyone with skin issues has tried a Jak inhibitor and how they found them for the skin?

[lovesradio]

I haven't tried these but there was an article in the recent Exchange (magazine from National Eczema Society) and it might be available on their website eczema.org

[Nikey92 in reply to lovesradio]

many thanks, I will take a look )

[Lizzo30]

Hi how old are you Nikey92 ?I am asking this to understand if hormones are playing a part in your eczema

[Nikey92 in reply to Lizzo30]

Hi Lizzo, I am a 48 yr old Male. Really at the end of my tether with my skin, hence why I paid up and went to see a private dermatologist. If you have any ideas I would love to hear ) My immune system just seems to be attacking itself which is causing my skin to be inflammed, I caught Covid in Feb this year and to be honest it hasnt been good since. Apparently this jak inhibitor medication is used to dampen down the immune system, like giving it a reset but targets specific areas linked to autoimmune conditions instead of switching it off completely but if I can avoid taking medications I would prefer.

[Lizzo30]

Hi Nikey92 I have had covid 3 times and what I learnt was that covid thrives in and creates an acidic environment which is inflammatory so I countered covid acidity with an alkaline diet a very cheap alkaline ingrediant with bicarbonate of soda I have half a teaspoon in water every day many people swear by alkaline water and an alkaline diet celery,cucumber and melon are alkaline and I find cider vinegar to be beneficial I have it in a salad dressing or on chips at any opportunity so going alkaline is the first line of defence imo against covid and long covid

too much alcohol can be acidic and so can too much coffee however I start the day with coffee bc it is also inflammatory it blocks estrogen - which is what fired up my eczema

So you probably know that boys usually get eczema worse than girls as kids but grow out of it at puberty whereas the opposite is true of girls bc too much estrogen can cause eczema and presumably testosterone suppresses the immume system and clears up eczema , given this you may be low on DHEA and or testosterone so you could maybe get them checked - probably privately as I don't think NHS test them and even if they did they don't prescribe testosterone

I am taking DHEA an androgen synthetic hormone myself atm the brand I use is Biovea you can buy it online I just take 5mg per day which is a very low dose I like it as an estrogen blocker bc it lifts your mood and makes you feel good yet it suppresses the immune system I strongly suggest you check it out

I hope this info is helpful to you Nikey29

[Nikey92]

Hi Lizzo,

Thanks so much for taking the time to provide me with so much useful information. I am a big believer in combating acidity in the body and I had previously purchased medical grade soda bicarb, I havent taken it for a while as I had concerns that it may raise sodium levels in the body but today I have started with a half teaspoon in glass of water.

Very interesting your comments regarding testosterone, I didnt know this acted to keep the immune system in check. I will look into getting my levels tested, not sure if this can be done via online but I will see what I can arrange. I have also found the Biovea DHEA supplement you have mentioned, it seems this could certainly be useful, I read with interest it can help with cortisol levels and cortisol being something that can cause inflammation, order placed for the 100mg tablets, I will give them a try.

Thanks again for your help, certainly gives me something to look into )