I do wonder how many cases of unexplained infertility are actually due to undiagnosed ET and the blood clots that can develop.
Is there any research on this?
When i was trying to conceive in my late 30’s ( I did eventually have a son) my MPN hadn't been diagnosed, but might well have been ticking away.
There are infertility specialists who routinely suggest that patients take a daily baby aspirin, just in case there are clotting problems but this is off label .
Rachelthepotter
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Gipsy123
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Hi Gipsy My daughter had her first baby prematurely and suffered all symptoms of pre eclampsia. I kept suggesting she ask about aspirin and possibly blood pressure medication throughout her pregnancy as to me she was small for dates.. but this was usually rejected as she was told she was progressing fine .. she ultimately was hospitalised at 29 weeks and baby delivered at 34 weeks after lots of medical interventions.
With subsequent pregnancy they did early intervention.. and no problems . She has Raynauds and can be hypertensive from young age but otherwise fit , i think possible other symptoms but as yet has been told by medics nothing to consider .. we are so complicated but when you see symptoms repeated .. an enquiring mind always gives these things consideration.L
Could be worth persisting. Asprin and blood pressure meds are cheap and effective. But irs hard to get one speciality to listen to another- and even harder to get listened to as a oatient…
Landtblom, A.R., Andersson, T.ML., Johansson, A.L.V. et al. Childbirth rates in women with myeloproliferative neoplasms. Leukemia 38, 1081–1085 (2024).
(I’ve only skimmed it) it looks as though this retrospectively looked at women with known MPNs and how that affected their chances of becoming parents. I wonder (after a long and difficult journey to parenthood) whether an emerging MPN contributed to our own difficulties, or perhaps conversely those problems (and treatment for them) contributed to changes that triggered JAk2 or other mutations. Could also all be coincidental!
There is so much overlap between women’s health and mpn symptoms that make it so hard for us and doctors to see the wood for the trees. I was very happy to see the very balanced MPNVoice presentation about the considerations for women experiencing (peri/) menopause and mpns.
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