Haven’t commented for a while as I seemed to have been locked out of the MSN comments, however I seem to be back now!! I have been taken off Hydroxycarbomide, which is a chemo drug, as I have ulcers and bad sores on my legs. I have been put on anagrelide started at 2 per day and it caused my platelets to rise to nearly 800, I am now taking 5 per day. This is giving me terrible headaches. I have been told I will be going back on Hydroxycarbomde, when the ulcers have gone. I have had ET for 28 years and am absolutely fed up with it now.