The new CALR drug, any new news?

[George1976]

I heard there is a new CALR drug coming for those of us with this type of MPN. Has anyone heard about it recently? I thought trials were beginning soon but there has been nothing in the news or on this message board that I’ve noticed. Thanks in advance!

[dbus1417]

I haven’t seen any trial data come back yet but my hematologist tells me it entered clinic this past summer so we should hear something soon. 🤞🏽

[Joetcalr in reply to dbus1417]

Thanks dbus, do you know the name of it? So I can keep an eye out.

Is it the one that’s like a vaccination?

[dbus1417 in reply to Joetcalr]

I think it is still going by its top secret code name INCA033989. It is a monoclonal antibody so I am unsure how the payload gets delivered..

Here is some information and an overview on what it is, what it does, and how it works.

investor.incyte.com/news-re...

I know the Covid monoclonal antibody was administered via IV. So I would assume the same for this but I am only speculating.

[Joetcalr in reply to dbus1417]

Thanks 🤞🤞

[flamboyant_hawking]

Their study completion date is in 2028., I don't think that drug will become available prior to that. There is a list of location recruiting patients, you might want to participate: classic.clinicaltrials.gov/...

[George1976]

thanks for the info!