Besremi

[josup26]

Hello all, I have been on Besremi for 6 months having excellent blood results. This past 10 days I started with bloating ,constipation and gas. Anyone had these issues? I have put a call into my Hemo team waiting to hear back.

Have a great day!

[Elizka]

I have not.

[hunter5582]

I have not experienced those side effects on Besremi, but they are listed as possible.

drugs.com/sfx/besremi-side-...

Hope you get this sorted out ASAP.

[josup26 in reply to hunter5582]

Thank you

[Anag]

I’m really sorry to hear that. I have been on.Besremi since October, and my thrombocytes have not gone down that much. The only thing I noticed is a bit of joint discomfort, or I have had previous injuries.

I do hope that your system are being caused by something else. For me, the biggest bloater was wheat and rye and white beans, even if they’re prepared and cooked properly.

I really hope it’s not Besremi! 🙂

Anag

[KLCTJC]

I haven’t had those issues from Besremi, but have been on miralax for years. And it has always helped, maybe not with gas, but great for constipation.

[Miriammusic]

I have been experiencing GI issues on Besremi. As Hunter noted, it is a listed side effect. My GI said that all interferons are known to be drivers of IBS. 🤷‍♀️

[josup26 in reply to Miriammusic]

Thank you

[Ggrana3192]

I have not had those issues and I’m doing 500mcg

[PhysAssist]

Hi Josup26,

While I have not had any discernible side-effects from my Besremi injections, I haven't gotten any stable reduction in my counts or Hematocrit either.

In fact, my Hct drawn yesterday had rebounded up to 51% despite my last Besremi injection being the 2nd time at 350 mcg just a week ago.

Good luck with the side-effects, but don't forget that because those symptoms are pretty much non-specific, even though they're listed as possible side-effects from the medication, it's pretty unlikely that they'd just pop up now after the previous 6 months of treatment without them- unless your dosage just changed dramatically.

Instead, they could represent any number of other less concerning things- like a viral GI bug, change in diet, or just a blip in your microbiota- any of which can be exacerbated by stress.

God bless and good luck,

Best,

PA

[josup26 in reply to PhysAssist]

I thank you for the reply,

I do think my GI issue was a fluke as I felt better in less than a week.

I'm sorry to hear you are having difficulty bringing down your HCT. I did have the problem when I first started Besremi. Then with my Hemo we started more aggressive approach. I had phlebotomies along with 200mg of Besremi. Over all I think I had 3 Phlebotomies then my HCT dropped to 36. At present my Besremi has been reduced to 100mg and my HCT holding 38-41 for 4 months.

I hope you find some cocktail that works for you.

Regards

[PhysAssist in reply to josup26]

Hi Josup26,

Thank YOU- I'm glad you're feeling better!

Best,

PA