Post by MPN-MATE Admin » Sun Feb 02, 2020 3:57 pm
JAN. 23, 2020
What's blood type got to do with clot risk?
Hey everyone... 
Earlier today I promised to put up this Post, as it may have some bearing as to why some of us have more BP & hypertension, and also clotting events, than do others... (?)
Could it be as simple as what 'Blood Type' we are???
Enjoy the read...
Best wishes
Steve
Thanks for this, interesting. I am blood type A but I also have high BP.
Very interesting - I am blood type A RhD Negative (Alien Blood)
Fascinating...
I wonder how many of us know our blood types and what they are ...And... IF? We are having exceptional issues etc...?
Steve
Type A+.
Me is A+
Amazing that so many with an MPN have an 'A' type... very curious and interesting too...
Apparently, having an 'A' Type might mean that you are more prone to High Blood Pressure (BP), and possibly clotting too...
All the more reason for everyone to have a special anti-inflammatory dietary regime and consistent exercise schedules too...
Anyways... fascinating all the same...
Best wishes
Steve
The only reason I know mine is due to having babies - I needed to have an Anti-D injection after delivery/miscarriage. My Mum has the same blood group as me as does one of my sisters. The other sister and my brother are A+.
I must remember to ask for mine.
Me too... 
Do you know yours Steve?
No, not as yet... But it is also interesting because I have recently learned I am VWS Type 2 as well... Which is lower levels than most, which might indicate I am on the O side of blood types...???
I will let you know as soon as I find out... 
Steve
Hmm, very interesting!
Very interesting. Another interesting factoid - people with type "O" blood also tend to have significantly lower levels of von Willebrand Factors. Came up when I was undergoing the full von Willebrand Disease evaluation. (I am O+)
Hey Hunter...
I recently learned I am VWS Type 2 as well... Will let you know mine shortly to see if this coincidence holds relevant etc... 
Steve
Will be interested to hear. Despite vWB factors dropping below norm, I did not test positive for vWBS. Do keep an eye on it though as factors seem tp dip when platelet levels rise.
I have been doing a Methotrexate (MTX) Trial to try to better manage my rising platelets over these past months...
...However, I believe that I have started to detect a possible ulcer around the outer heal of my left ankle. Both ankles have been burning for some time, and now the skin has become notably irritated on my lefthand side...
Hence, I have just ceased taking the MTX to try to determine if my ankles return to their normal disposition etc... (?)
However, the consequences of such actions will of course possibly mean Platelets back on the rise again, and VWS antigen levels bottoming out as well (?)
I am presently looking into the benefits & liabilities of Navitoclax for Platelet management... (?)
Speak more soon when I learn of my own Blood Type etc...
Steve
Well dagnabbit! Sorry to hear those woes. I do get that given the vWB issue platelet control is needed. Hopefully some of the emerging treatments will prove helpful. I know you stay on top of the research. Perhaps one will work for you.
Will still try to get Down Under at some point. Want to come visit my nephew in Sydney, see the Outback, and pop over to New Zealand - just because.
Going to have to deal with the bone tumor just found on my jaw, but heck - after a brain tumor a mandible bone tumor seems like relatively small potatoes. Still trying to sort out the impact of having a Rasopathy (neurofibromatosis type 1) along with the JAK2 mutation. Two kinase-based disorders in different kinase systems that talk to each other - aren't I lucky!? Neoplasms abound apparently.
Oh well - Hooroo my friend.
Hey Hunter...
Will be very cool to see you in Sydney. Please do provide me with some warning and I shall make sure we arrange a Cafe Catchup during your stay. I am sure others would be delighted to meet with you too...
Stay in touch buddy...
Steve
what does VWS mean? Thanks
Von Willebrands Syndrome (VWS)
Is also known as Von Willebrands Disease (VWD)
Von Willebrand disease (VWD) is a genetic disorder caused by missing or defective von Willebrand factor (VWF), a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process. The condition is named after Finnish physician Erik von Willebrand, who first described it in the 1920s.
Lucky
Good thing that surgery went well. Turned out to be a lipoma with osseous metaplasia. Not a big surprise as this is the 7th lipoma I have had removed, just the first that was converting into bone tissue. It is gone now. Yay!
Good news!
Hmmm. See a lot of type As which I always thought was not so common. I’m A- myself.
How interesting, I’m A+ too! So we all know where to go if we need blood. 😂
Hi I'm also A-
Interesting research. I am B Rh+ and have had PV JAK+ for nearly 5 years. I had two leg DVTs last year, treated for 6 weeks with rivaroxaban. Clear now. I wonder if I will get a recurrence if the DVT risk is higher - but I am not going on sweat on it.
Yet another appears to suggest that this theory might well be factual...
I wonder how many people out there, I mean what percentages might indicate?
Blood Type obviously is a factor worth some further considerations...
Thank you for responding ...
Best wishes
Steve
Yes that’s weird I’m also A+ had ET for a long long time, makes you wonder doesn’t it ?
Hey Chemo01...
Yes, more proof in the pudding...
Thanks for responding...
Best wishes
Steve
Gracious I am an A+ too. Just something more to worry about😩Jak2 ET since 2019 and now progressed to PV It all causes lots of anxiety but just have to keep going and reading all the stories of others here
Margo
Thanks Margo...
Keep smiling... It might just help us to learn these things are also part of the unique variables that go toward making our MPNs so diverse etc...
Stay happy & well...
Steve
It looks like lots of A’s. I am different ... I have ET and am O -. Wish I knew what my sister’s type was . She had PMF and passed 11 years ago .
Hey Cookiebaker...
Interesting too that you have others in your family with an MPN...
'O' Types might mean that you are at less risk of both Blood Pressure (BP) & clotting problems... maybe... ???
Best wishes
Steve
I haven’t had clots but do have high blood pressure!!
Interesting. Also blood type A+, but low VWF - thus bleeding risk rather than clotting, normal BP. Early (prefibrotic) grade 1 MF, Jak 2+, proliferative stage.
Hey Lab-Rat...
Love your handle by the way...
Yes, I too feel like a Lab Rat myself most of the time.
My VWS levels are usually lower than they should be, and apparently that will often coincide with Platelets being over the 800 mark...
When Platelets reduce back below 800s, then VWS levels are believed to return to normal levels also...
Well at least in my case...
I too have experienced many bleeding episodes throughout my journey, but not usually too serious in nature... More just disturbing etc...
Really MUST find out what my own Blood Type is too... ???
Best wishes
Steve
I’m B negative- ET jak 2+ had a bilateral pulmonary embolism x
Thanks Mallard...
It is an interesting piece of research is it not?
Stay safe & well...
Steve
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