Since I was diagnosed in early 2014 so many things have changed for me personally. I never had any health issues prior to having ET. Am I just down on luck or have others had such a drastic change? Since diagnosis I have elevated blood pressure, elevated cholesterol, hypothyroidism, tibia and peroneal neuropathy, vision changes, major fatigue, deep leg pain to name a few. I'm too young for this! It gets very depressing some days. I started on Anagrelide but after about a year and a half I was switched over to Hydrea of which I take 1,000 mg every day with baby aspirin. My arsenal of medication has gone from 1 vitamin to too many to list.