Yes, or groin! Have only been able to get 250ml out of me recently instead of me generously supplying 500ml as usual. Opted to continue with the Venuses (call them this cos I love 'em......not!) & daily Clopidogrel (asthmatic so can't do the aspirin bit) instead of going on to Hydroxy. Got scared when he labelled it oral chemo but it seems some of you haven't had any adverse reactions only felt benefits? Would welcome you sharing your experiences so I can make an informed choice. Thanks.