Has anyone tried to come off this drug? I have been on it for about a year after a hospital admission for psychotic depression. Last week I decided to go cold turkey this was a big mistake as I got palpatations, increased anxiety and confusion. Would be really good to know if anyone had been through coming off this drug?. I also take 375 venlafaxine and 30 mirtazapine. But I'm going to stay on these for now as I don't want to risk another hospital admission.