High ANA (antinuclear antibodies)

[hawkis]

Hello, I am new in this group, but have been searching for answers for years about chronic fatigue.

Over a decade ago, I thought I'd found the answer as I was diagnosed with a B12 deficiency, which is now supplemented with regular injections. For a few years this helped, but the last few years again, it's been getting much worse, so I am now struggling to cope with daily family life.

CFS has been discussed and many many blood tests have been made, and I have seen neurologist/immunologist/gastroenterologist/endocrinologist consultants.

One constant peculiarity which all these consultants have said is very unusual is I have a very high ANA result which has increased over the past 6 years and now remains very high, at a dilution 1:5120.

The result can not be attributed to other specific autoimmune antibodies or a specific disease. Is there anybody else, out there who has a persistently high ANA result? And if so, has a doctor given any advice about it?

Thank you for any insights you can share 🙏🙂

[Beefull8]

hi I also have high ANA that recently went up after I had covid and then long covid. I think it is related and I also think I had CFS undiagnosed for years. I also have autoimmune thyroid but my ANA was stable for years until I got covid. My doctors don’t know why it went up and referred me to a rheumatologist but I haven’t yet been called for an appointment.

[hawkis in reply to Beefull8]

Thanks for your feedback, I hope you can get some answers and not feeling too awful. It's hard to find answers. Take care 🙂

[strongmouse]

Hello, the ME Association have some information on Long Covid and CFS, which you might find helpful. They have a helpline as well - meassociation.org.uk/long-c...

[klr31]

I have this too, and have M.E and Hashimoto's. It often indicates autoimmune disease of some description.

Karen

[MayGodBlessYou]

interesting, i don't know if i've had any ANA test.

with b12 treatment, sounds good, except sounds like it reduced tiredness,

so then you went and were able to do more things,

and then it was a trap and has become exhausting.

it's so easy to overdo.

i do it daily.

i read on forums that people would start something move, like low dose naltrexone;

it would be great for some weeks;

then they would report that they were exhausted again.

so our bodies either develop a tolerance to the help,

or,

we feel a bit better then do a bit more, then crash.

take care

[Pieface1]

I have high ANA and my consultant at one time (years ago) wanted it retesting to check accuracy. I saw the GP to request the retest and he called me manipulative. I have read that a high ANA on its own is meaningless, so GPs ignore it.