I have always been ana positive in the past and my recent one was negative which puzzled the rheumatologist, as I have been suffering from increased inflammation which showed in my bloods. I have been feeling dreadful and she says it's due to increased lupus activity. Has anyone else had this happen and know why this would be??
From ana positive in past to ana negative?? - LUPUS UK
From ana positive in past to ana negative??
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Caramia1964
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Possibly a false negative?
ANA tends the fluctuate and is generally not used as a marker to follow disease activity after you are diagnosed. My rheumatologist used complements C3 and C4, anti-dsDNA which are better indicators of lupus activity.
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