Immunoglobulin numbers changing - Flare?

[katidid]

Hi all,

A few months ago I got sick. I actually thought it was an infection since some of my more regular flare symptoms were mild or not present for the first two weeks and then I felt better until crashing again. It’s been 2 months of 80/20 awful to “bleh” days.

Randomly we decided to test my: IgG, IgM and IgE levels. Compared to historic results, G and M were way off. Both too high.

I had come down with CDiff (again) one month into feeling bad, but I’ve been on therapy and that infection has resolved.

So, out of caution they did the blood serum COVID-19 test. Thankfully it was negative - our precautions have been successful!

So, my doctor and I are wondering if the change in immunoglobulin levels is another way of identifying and monitoring my Lupus flares. IgG is a known player, not sure about IgM.

They aren’t a way to measure my Spondylitis status, but a SpA flare is so easy for me to peg I’m not concerned. It’s the SLE that is always more muddy. It’s hard when you have multiple things, especially when the cross over symptoms are so hard to discern.

I’m thinking that I ask to add IgG and IgM on to my run of the mill autoimmune blood monitoring.

Does anyone else do this? Thoughts?

Here’s the latest flower pic as promised (although belated!)

Does anyone

[Hidden]

My IgG and IgA are always high. I was told it’s due to polyclonal gammopathy relating to my overlap mix of CTDs. I don’t get to choose which tests they run unfortunately so I only get these looked at once every year or two. The IgA always remains high but the IgG comes down to top of range when I’m immunesuppressed.

[katidid in reply to Hidden]

Thanks for the info!!