I've been on prednisolone for almost exactly a year now. In that time, I've developed severe daily episodes of sweating, tachycardia, nausea and shaking. Even more debilitating has been the profound fatigue.
Neither my rheumatologist, respirologist, cardiologist nor GP have been able to offer any explanation for these symptoms - although my rheumy has suggested that I have developed fibromyalgia, and my GP has referred me for a neurological opinion.
I believe that an imbalance in my cortisol/prednisolone metabolism is responsible. So in January, after discussion with my medics, I decided to try and taper my steroids off completely. They have kind of given a collective shrug and said, "We're all out of ideas, so give it a go".
I have taken it slow, as per medical advice (actually, rather slower than my rheumy suggested) and I've now got down to 4.5 mg daily.
So far, it's been interesting. The first day I take a reduced dose, I feel much better. This can last for up to a week, and I realise what life is like when you don't feel like $%^ . It's fabulous! Then there's a kind of rebound and the old symptoms return. I'm doing regular peak flow readings - as my lungs were the biggest issue originally - but they have done so well that my resp consultant has just decided he doesn't need to see me again unless my rheumy requests it (*touches wood*). In other words, so far, there's been no downside.
Anyway, at 0.5mg every fortnight, it will take me till August to hit zero. Until then, I'll make a little diary entry here every couple of weeks, in case anyone might be interested.