Methotrexate: Just started methotrexate with my... - LUPUS UK

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Methotrexate

diane46 profile image
7 Replies

Just started methotrexate with my first dose don't know how I feel

I think I feel sick and dizzy is this normal after only one dose

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diane46 profile image
diane46
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7 Replies
AnnNY profile image
AnnNY

Yes.A lot of people take it at night, so the won't feel the side effects and before two days when you can be a little extra tired. Are you taking folic acid. It can reduce the side effects, but discuss that with your doc. It also can take some time to work. For me it was amazing to be completely out of pain for the first time in thirty years, but the fatigue was too bad for me to continue it.

diane46 profile image
diane46 in reply toAnnNY

Yes I am taking folic acid but I didn't think it would hit me after one dose thanks

AnnNY profile image
AnnNY in reply todiane46

For me I had fewer side effects the longer I took it as far as nausea. The fatigue that was what was unacceptable to me.

misty14 profile image
misty14 in reply todiane46

Hi Diane

Are you taking folic acid each day except the day that you take the Methotrexate dose?. Hope it soon settles for you and you get the benefits. X

Taweet profile image
Taweet

Hi Diane-I do remember feeling awful for the first couple of weeks on Methotrexate-but hang in there it does get better with time. I have been taking it now for 8 years and on "drug day" still feel not quite myself but by the next day I feel fine. The overall benefits far out way the minimal side effects in the end, I wouldn't be without it :-)

loopy-lou profile image
loopy-lou

I take it late afternoon. I can feel wiped out on and off over the next 48 hours. I also had bad nightmares when I first started taking it and it has happened each time the dose was increased. I have been better since taking it but there is still room for further improvement. I hope you feel better soon.

diane46 profile image
diane46

Thanks feel better today not sick and have eaten todays but still feel funny

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