Yesterday I was really hormonal and I was in agony, didn't sleep well with the pain and took extra tramadol during night even though at night I take 100mg slow release. Still in pain now and tramadol is not helping much. Not diagnosed lupus fully, rhumy mow says lets say fibromialgia connective tissue dissorder with a side order of arthritis, underactive thyroid and pernicious anemia thrown in to the mix. Anyway hormones.... any ideas??