My last scan at the end of June made it official: no new spots, but everything is growing. I had already had a biopsy with a removal of a lymph node by that time so that we could get a comprehensive genomic analysis of where I'm at right now. The past month has been an exercise in patience as I waited for Foundation One results.
The results took me by surprise. Tagrisso has worked so well, it has completely wiped out all the cells that had the T790M mutation. I still have the EGFR exon 19 deletion. Now it has a couple of new friends - BRAF and PIK3CA. I've been doing research in earnest and it appears that an EGFR/BRAF combo is quite unusual. (I bet that as more people come off of Tagrisso, it might become less rare.)
My oncologist at Roswell has found one clinical trial in all of the US that might fit my situation - a combo of Tarceva and a MEK inhibitor way down in Florida, at Moffitt. She also says my cancer is growing slowly enough that we can gather some more information before deciding on what my next treatment. I'm feeling good, which reinforces taking some time and staying on Tagrisso at the current time.
I hope to have another blog post soon.